王朝英
汉族，副教授，理学博士。
工作经历：
2026.1 - 至今 bv伟德中国官方网站 副教授
2020.7 - 2025.12 bv伟德中国官方网站 讲师
2018.8 - 2020.7 瑞典哥德堡大学 博士后
2016.8 - 2018.7 清华大学 博士后
教育经历：
2011.9-2016.7 中国科公司化学研究所 博士
2012.4-2013.10 太平洋西北国家实验室 访问学者
2007.9-2011.6 东华大学 学士
通信地址：理工楼0116，北京市海淀区中关村南大街27号，100081
邮箱：zhaoying.wang@muc.edu.cn
讲授课程
分析化学、分析化学实验、质谱成像与代谢组学等。
主要研究方向
飞行时间二次离子质谱（ToF-SIMS）仪器研制及单细胞空间分辨代谢组学分析方法研究与生物应医学用。
承担纵向科研项目
2022.11-2027.10 单细胞代谢组高通量定性定量及高分辨成像分析,国家级，课题负责人，国家重点研发计划青年科学家项目，2022YFC3401900，500万（bv伟德中国官方网站100万）
2022.1-2024.12 基于微流控芯片与飞行时间二次离子质谱的冷冻单细胞三维质谱成像方法研究，国家级，主持，国家自然科学基金青年项目，22104160，30万元
2026.1.1-2028.12.31 基于质谱成像的单细胞代谢分子识别方法与应用研究，省部级，主持，北京市自然科学基金面上项目，20万元
2017.2-2018.8 真空紫外质谱原位监测神经元细胞神经递质的释放过程，国家级，主持，中国博士后科学基金第61批面上资助, 2017M610860,5万
代表论文
1) C. Qi, X. Li, Q. Li, X. Shi, M. C. Xia, Y. Chen, Z. Wang*, Z. Abliz*. 2024. Mass Spectrometry Imaging for the Characterization of C═C Localization in Unsaturated Lipid Isomers at the Single-Cell Level, Anal. Chem. 96, 15085-15090.
2) X. Shi, X. Li, Q. Li, C. Qi, M. Xia, Z. Wang, Y. Chen, Z. Zhou, Z. Wang*, Z. Abliz*. 2024. A ToF-SIMS methodology for analyzing inter-tissue lipid distribution variations and intra-tissue multilevel mass spectrometry imaging within a single rat, Microchem. J. 200:110235.
3) J. Bai, C. Li, M. Qian, X. Ding, Q. Li, Y. Chen, Z. Wang*, Z. Abliz. 2025. Norm ISWSVR Enhanced Data Repeatability and Accuracy in Large-Scale Targeted Quantification Metabolomics, J. Am. Soc. Mass. Spectrom. 36, 1027-1033.
4) X. Shi, M. Liu, Y. Qi, H. Ma, Z. Wang*, Y. Chen, Z. Abliz. 2025. A laboratory-friendly protocol for freeze-drying sample preparation in ToF-SIMS single-cell imaging, Front. Chem. 13, 1523712.
5) H. Ma, M. Liu, Y. Zhang, M. Sun, Y. Chen, Z. Wang*, Zeper Abliz. 2025. Freeze-drying enhances ToF-SIMS imaging of biological tissues via structural and metabolic preservation, Anal. Methods. 17, 5480-5488.
6) M. Sun, H. Ma, M. Liu, M. C. Xia, Y. Chen, Z. Wang*, Z. Li. 2025. ToF-SIMS Imaging for the Analysis of Cholesterol Formation at Macrophage Membrane. Metabolites.15, 722.
7) M. Liu, H. Ma, X. Fang, Y. Chen, Z. Wang*, X. M. 2026. Norm-SVR for the Enhancement of Single-Cell Metabolomic Stability in ToF-SIMS. Metabolites. 16, 36
8) Z. Wang, X. He, K. Long, A. G. Ewing. 2021. Electrochemical and Mass Spectrometric Measurement of Enhanced Intravesicular Catecholamine Content and Exocytotic Frequency at Subanaesthetic Ketamine Doses, Anal. Sens. 1, 166-170.
9) Z. Song+, Z. Wang+, H. Zhao, L. Cai, Z. Li, S. Zhang, X. Zhang*. 2020. Metabolic fingerprinting of cell types in mouse skeletal muscle by combining TOF-SIMS with immunofluorescence staining, Analyst, 145(21): 6901-6909.
10) J. Wang+, Z. Wang +, F. Liu, L. Cai, J. Pan, Z. Li, S. Zhang, H. Y. Chen, X. Zhang* & Y. Mo*. 2018. Vacuum Ultraviolet Laser Desorption/Ionization Mass Spectrometry Imaging of Single Cells with Submicron Craters. Anal. Chem. 90:10009-10015.
11) Z. Wang+, Y. Zhang+, B. Liu, K. Wu, F. Wang*, Z. Zhu* et al. 2017. In Situ Mass Spectrometric Monitoring of the Dynamic Electrochemical Process at the Electrode-Electrolyte Interface: a SIMS Approach. Anal. Chem. 89: 960− 965.
12) J. Wang+, Z. Wang+, F. Liu, L. Cai, S. Zhang, C. Sun, R. Zhang, Z. Abliz, Y. Mo*, X. Zhang *. 2018. Mass Spectrometry Imaging of Intact Cholesterol in a Mouse Esophagus Tissue Section and Mouse Zygotes Using VUV Laser Desorption/Ionization Method. Int. J. Mass. Spectrom.432:9-13
13) Z. Wang, J. Liu, M. Hong, B. Liu, F. Wang*, Z. Zhu*. 2016. Nanoscale Imaging of Li and B in Nuclear Waste Glass, A Comparison of ToF-SIMS, NanoSIMS, and APT. Surf. Interface Anal. 48: 1392-1401
14) Z. Wang, B. Liu, W. Zhao, K. Jin, F. Wang*, Z. Zhu* et al. 2015. Argon Cluster Sputtering Source for ToF-SIMS Depth Profiling of Insulating Materials: High Sputter Rate and Accurate Interfacial Information. J. Am. Soc. Mass. Spectrom. 26: 1283-1290
15) Z. Wang, K. Jin, Y. Zhang, F. Wang*, Z. Zhu*. 2014. ToF-SIMS Depth Profiling of Insulating Samples, Interlaced Mode or Non-interlaced Mode? Surf. Interface Anal. 46: 257-260
